Focus of Work
I have a clinical translational interest in Cystic Fibrosis. I am the site co-PI fo...[Read full text]My primary research interest is in lung repair after acute injury with a focus on TGF-beta mediated signaling. We have identified mitochondrial generated reactive oxygen species as important in TGF-bête mediated gene expression and are working to identify novel therapeutic targets in this pathway. We are also interested in modulating the ubiquitin-proteosomal pathway as a therapeutic target for tissue fibrosis.
I have a clinical translational interest in Cystic Fibrosis. I am the site co-PI for the CF Foundation sponsored clinical trial network, The Therapeutic Development Network. I am also interested in the CF outcomes, especially related to chronic infection with Pseudomonas aeruginosa.[Shorten text]
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Education and Certification
- MD: University of Chicago (1989)
- Internship: University of Chicago Pritzker School of Medicine, Internal Medicine (1990)
- Residency: Univ. of Chicago Hospital, Internal Medicine (1992)
- Fellowship: University of Chicago, Pulmonary & Critical Care Medicine (1996)
- Board Certification: Critical Care Medicine, Internal Medicine, Pulmonary Disease
McGaw Pavilion Suite M-300
240 E Huron
Chicago IL 60611
Institutes and Centers
View the Manu Jain Northwestern Scholars profile.
Northwestern Scholars is a searchable database of research expertise across all disciplines at Northwestern University. You can view collaboration networks among researchers within Northwestern and with external scholars.