Read the latest news from Northwestern University Feinberg School of Medicine’s Department of Medicine. The links below take you to articles where you can learn more about our faculty’s latest achievements, awards, and honors.
- 11.15.2017 - ResearchGenetic mutation in extended Amish family in Indiana protects against aging and increases longevity. Douglas E. Vaughan, MD, Chairman of the Department of Medicine is the lead author of the paper who has been studying PAI-1 for almost 30 years.
- 11.08.2017 - Hematology-OncologyAlicia Morgans, MD, MPH receives 2017 PCF Challenge Award for her project SEARCH: Survivorship Enhancement in Men with Prostate Cancer At Risk for Poor Cognitive Health During Treatment with ADT.
- 11.06.2017 - Rheumatology
- 11.06.2017 - Gastroenterology and HepatologyA treat-to-target strategy using “tight control” of inflammatory biomarkers in addition to clinical symptom monitoring led to improved outcomes in patients with Crohn’s disease on Humira, according to data from the CALM study presented at UEG Week.
- Congratulations to Dr. Rosalind Ramsey-Goldman on Receiving the Evelyn V. Hess Award from the Lupus Foundation of America11.06.2017 - Rheumatology
In 2005, The Lupus Foundation of America established the Evelyn V. Hess, MD, MACP, MACR, Award, to be given annually to a clinical or basic researcher whose body of work has significantly advanced understanding of the pathophysiology, etiology, epidemiology, diagnosis, or treatment of lupus. This award was created to recognize Dr. Hess' outstanding contributions to lupus research over the course of her long career. We are proud to have Dr. Ramsey-Goldman's contributions to the lupus community recognized! More information on past award recipients can be found on the Lupus Foundation of America's website.
- 11.02.2017 - Hematology-Oncology
An international team of scientists has pinpointed the genetic drivers of diffuse large B-cell lymphoma — the most common type of blood cancer — and determined the genes’ clinical significance. The study, published in the journal Cell, provides important insights for the development of future therapies.
Leo I. Gordon, MD, the Abby and John Friend Professor of Cancer Research, was a co-author of the study.
- 10.31.2017 - Hematology-Oncology
Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.
The mechanism -- RNA suicide molecules -- can potentially be developed into a novel form of cancer therapy, the study authors said.
Cancer cells treated with the RNA molecules never become resistant to them because they simultaneously eliminate multiple genes that cancer cells need for survival.
“It’s like committing suicide by stabbing yourself, shooting yourself and jumping off a building all at the same time,” said Northwestern scientist and lead study author Marcus Peter. “You cannot survive.”
- 10.27.2017 - Infectious Diseases
Congratulations to Michael Angarone, DO, and assistant professor of infectious diseases at Northwestern University's Feinberg School of Medicine, on achieving the John X. Thomas, Jr. Best Teachers of Feinberg Award 2017! Kudos to you on your award. The Division of Infectious Diseases very much appreciates all your hard work with medical students.
- 10.27.2017 - Allergy-ImmunologyNew research has found that almost half of people diagnosed with food allergies developed this condition in adulthood, with Hispanic, Asian, and black individuals most at risk.
- 10.27.2017 - General Internal Medicine and Geriatrics
A joint study co-authored by Jeffrey A. Linder, MD, MPH, at Northwestern University's Feinberg School of Medicine, and Jason Doctor, chair of the health policy and management department at the University of Southern California-Los Angeles, was recently published in JAMA. The study focused on making doctors aware of how frequently they prescribe antibiotics compared with their peers and how this might be the most effective way to prevent unnecessary antibiotic prescriptions in the long term. Dr. Linder, co-author of the study and the Chief of the General Internal Medicine and Geriatrics division said the findings indicate hospital systems should consider implementing similar interventions on a long-term basis. "Doctors are people too and we want to be liked by people, and we want to do well relative to our colleagues," he said. "Why shouldn't doctors respond to the same sort of peer comparisons and social norms that everyone does?"
- 10.27.2017 - Rheumatology
The Department of Medicine congratulates those honored at the he seventh annual Medical Education Day, held at the Northwestern Conference Center at Feinberg Pavilion.
John X. Thomas, Jr. Best Teachers of Feinberg Awards
- Mike Angarone, DO, assistant professor of Medicine in the Division of Infectious Diseases and of Medical Education
- Margaret Chapman, MD, assistant professor of Medicine in the Division of Hospital Medicine
- Kathryn Hufmeyer, ’11 MD, ’14 GME, assistant professor of Medicine in the Division of General Internal Medicine and Geriatrics
- Robert Kushner, MD, professor of Medicine in the Division of Endocrinology, Metabolism, and Molecular Medicine
- Toshiko Uchida, MD, associate professor of Medicine in the Division of General Internal Medicine and Geriatrics and of Medical Education
FAME Outstanding Teacher Awards
- June McKoy, MD, JD, MBA, ’01 GME, associate professor of Medicine in the Division of General Internal Medicine and Geriatrics and of Preventative Medicine
- 10.27.2017 - Infectious DiseasesMandy Stadtmiller in the Daily Beast writes that the STD epidemic in the U.S. will be getting much worse. The CDC in its annual Sexually Transmitted Disease Surveillance Report reported that for the third year in a row the cases of the top three tracked STDs in America: chlamydia, gonorrhea, and syphilis, are rising. While HIV rates nationwide were declining in 2016, several U.S. cities, including Miami, Atlanta, New Orleans, and San Antonio, continue to see an alarming rise in HIV infections. The CDC recommends that everyone get tested for STDs at least once in their lifetime. Public health experts caution that proposed federal cuts to STD funding will cause STD rates to skyrocket, much more infertility, and billions of dollars in health care costs. Public health experts seek a return to the same levels of STD-prevention funding as occurred in the 1990s and hope for a $40 million STD-prevention budget for 2018. During the 1990s when STD prevention funding was emphasized, the U.S. almost completely eradicated syphilis. Recently, however, 52% of STD prevention clinics have faced budget cuts. The U.S. now sees all known treatments starting to fail for some cases of gonorrhea. Michael Angarone, DO and assistant professor of infectious diseases at Northwestern University's Feinberg School of Medicine, states that drug-resistant bacteria [for gonorrhea] has started to appear in the U.S. Angarone adds, "So not only do you have this issue where we're seeing more cases of infection, now we're starting to see and get concerned about growing resistance to the treatment that we have."
- 10.26.2017 - Infectious Diseases
From a study involving 34 healthcare professionals who wore either long-sleeve coats or short-sleeve coats while interacting with mannequins to simulate patient care, it was found that no transmission of pathogens occurred when doctors wore short-sleeved coats. The healthcare professionals examined either a mannequin contaminated with cauliflower mosaic virus DNA or an uncontaminated mannequin.
Michael Angarone, DO, and assistant professor of medicine in infectious diseases at Northwestern University's Feinberg School of Medicine points out that although the virus contamined those wearing long-sleeve coats more often than short-sleeved coats, only one case of transmission to an uninfected "patient" occurred. Morever, Angarone states that "there may be a risk when wearing long sleeves, but it does not prove that long sleeves are transmitting pathogens to uninfected persons." He advises all healthcare professionals to maintain "regular and consistent use of hand hygiene practices" as a best practice.
- 10.23.2017 - Cardiology
Featuring: Neil Stone, MD
- 10.23.2017 - Infectious DiseasesLisa Rapaport with Reuters reports from a study on medical error causing serious injuries that patients want their doctors to listen to them and explain what safety measures the hospital is implementing to prevent the same medical error from reoccurring. The study was comprised of 27 patients, 3 family members, and 10 staff members at three different U.S. hospitals. A total of 27 of the 30 patients and family members from the study received compensation. Patients who experienced medical errors reported a strong preference for doctors listening to them instead of talking about treatment and communicating medical information. Of the 30 participants in this study, 24 reported that they did not receive information about safety improvements. Gary Noskin, MD, senior vice president and chief medical officer at Northwestern Medicine and professor of medicine within Infectious Diseases at Northwestern University's Feinberg School of Medicine, was not involved in the study and explains how this new finding contrasts with the typical response from hospitals after medical errors: “Traditionally, hospitals follow a ‘deny and defend’ strategy providing a paucity of information to patients." He also adds that open [communication] after medical errors may prevent litigation. Physicians practicing active listening instead of talking after a medical error may prove both meaningful to patients and advantageous to hospitals.
- Northwestern Launches NIH-Funded Center for Prevention and Treatment of Rheumatic and Musculoskeletal Conditions10.13.2017 - Rheumatology
- Rheumatic and musculoskeletal conditions affect a large portion of the U.S. population.
- The CCCR is centered on improving how persons feel and function in their daily lives.
- The CCCR will build upon the wearable and portable technology revolution and integrate several outstanding programs at NU.
A new five-year grant from the National Institutes of Health (NIH) will provide infrastructure to scientists and investigators at Northwestern University to support, accelerate, and improve the quality and impact of clinical research aimed at preventing or treating rheumatic and musculoskeletal conditions.
The funding, from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), supports the creation of the Core Center for Clinical Research at Northwestern University (CCCR). NIAMS created this grant specifically to condense the time between an investigator conceiving of a way to prevent or treat someone with rheumatic or musculoskeletal conditions and that intervention being incorporated into patient and population care. Rheumatic conditions include osteoarthritis, rheumatoid arthritis, other types of arthritis, lupus, systemic sclerosis/scleroderma, and vasculitis. Musculoskeletal conditions include any conditions that affect the joints, bones, muscles, ligaments, tendons, and injury to these tissues.
Improving how people feel and function in their daily lives
Specifically, under the leadership of PI Leena Sharma and Coinvestigators Michael Bass, C. Hendricks Brown, Rowland W. Chang, Joan S. Chmiel, Dorothy Dunlop, Hassan Ghomrawi, Monique Hinchcliff, Kristi L. Holmes, Masha Kocherginsky, Julia Lee, David C. Mohr, Richard Pope, Rosalind Ramsey-Goldman, Nan Rothrock, Bonnie Spring, Linda Van Horn, and Deborah Winter, the CCCR’s work will focus on prevention strategy and intervention development to create lifestyle, behavioral, medical, and rehabilitative solutions for individuals with or at risk for these conditions. These conditions affect a very large segment of the U.S. population. For example, an estimated 21 million Americans have diagnosed osteoarthritis, just one of the conditions that the CCCR targets. Considering just the knee, among Americans 55 years and older, 40% have frequent knee pain or radiographic knee osteoarthritis. In older individuals, knee osteoarthritis is responsible for as much chronic disability as cardiovascular disease.
The Center will support studies of persons throughout the lifespan, from childhood through old age, with the overarching goal of improving outcomes for those persons at risk for these conditions or who are already afflicted.
Providing research support to all collaborators
The overall aims of the CCCR are as follows:1. Accelerate and enhance funded research, by improving efficiency, rigor, collaboration, cost-effectiveness, productivity, and impact – this Aim deals with already funded research at Northwestern
2. Catalyze and add value to all NU research relevant to our mission – this Aim also deals with work that is already planned or underway
3. Promote new research, by expanding the community working in the areas of our mission and by expanding research fields within the mission – this Aim deals with work that has not as yet been envisioned
The CCCR is comprised of Administrative, Methodologic, and Resource Cores:
The Administrative Core is responsible not only for management and operations of the Center, but also for specific CCCR missions, some of which are organized into 3 Sub-Cores: the Mentoring Sub-Core will take charge of Administrative Core missions relating to scientific and career development of mentees, mentor development, and team cohesion; the Outreach Sub-Core will take charge of communication and enrichment missions, attracting investigators, furthering collaboration, and expanding the Research Community and fields of work; the Evaluation Sub-Core will be responsible for ongoing assessment of CCCR activities,
The Methodologic Core aims include, to provide: data management support; expertise pertaining to research design, study conduct, outcome assessment, and data analysis; an enhanced training environment through focused services, collaboration, team science training; cutting-edge capabilities to meet ongoing and evolving needs of the Research Community regarding: a) statistical analysis, b) epidemiology, c) behavioral science, d) nutritional science, e) implementation science, f) economic evaluation, g) genomics/bioinformatics, and h) clinical informatics.
The Resource Core, ASSIST-Daily Life (Assessment & Intervention Science & Technology in Daily Life), will integrate Sub-Cores (Person-Centered Outcomes Assessment and Technology; Accelerometer Measurement of Physical Activity, Sedentary Behavior and Sleep; and Behavioral Intervention Technologies), with these aims: design tailored multi-modal assessment and health interventions, incorporating real-world: a) self-report of social, physical, and mental health, symptoms, and life satisfaction, and performance-based assessment of motor, sensory, and cognitive function; b) accelerometry to assess physical activity, sedentary behavior, and sleep; and c) mobile, web, tablet, and sensor-based applications that identify real-world behavioral markers using GPS, activity logs, and wearable biosensors, to predict physiological and psychological states; and implement technology platforms that can deploy interventions and administer multi-modal assessment, integrating into the platform self-report, performance-based, and accelerometer assessment.
The CCCR is funded by NIH NIAMS grant P30AR072579. The Center will operate as an integrated unit, drawing on many outstanding departments and divisions across Northwestern’s Feinberg School of Medicine: the Departments of Medicine, Preventive Medicine, Medical Social Sciences, Physical Medicine and Rehabilitation, Physical Therapy and Human Movement Sciences, the Institute for Public Health and Medicine (IPHAM), and the Northwestern University Clinical and Translational Sciences Institute (NUCATS).
Congratulations to the Northwestern CCCR team!
- 10.12.2017 - Allergy-ImmunologyOn Tuesday, Nationals manager Dusty Baker said ace Stephen Strasburg wouldn’t start because the pitcher was under the weather, citing the change in climate, the hotel air conditioning and Chicago mold. On Wednesday, Baker changed his story and started Strasburg against the Cubs in Game 4 of the National League Division Series.
- 10.05.2017 - CardiologyFeaturing: R. Kannan Mutharasan, MD
- 10.02.2017 - Infectious DiseasesBritish researchers may have found a link between mood and flu shot efficacy, especially in adults over 65. It is possible that being in a good mood when one receives the flu shot improves his/her chances of protection from the flu. Michael Ison, MD, professor in Infectious Diseases and Organ Transplantation at Northwestern University's Feinberg School of Medicine, however, warns against waiting until one is in a good mood to receive a flu shot. Ison recommends that people get a flu shot when it is offered regardless of what kind of mood they are in.
- Northwestern Memorial HealthCare named to Working Mother "100 Best Companies" for the 18th Consecutive Year09.27.2017Northwestern Memorial HealthCare (NMHC) has been recognized by Working Mother magazine as one of the 2017 "Working Mother 100 Best Companies" for its outstanding leadership of women's advancement in creating progressive programs for its work force, such as flexible work hours, convenient and affordable child care and paid parental leave. This is the 18th consecutive year that NMHC has been recognized.
- 09.25.2017 - Rheumatology
- 09.25.2017 - Rheumatology
- 09.25.2017 - General Internal Medicine and Geriatrics
A study by Michael Wolf, PhD, MPH, professor of Medicine and Medical Social Sciences, was recently noted in the Washington Post: Research shows that seniors tend to prioritize other medical conditions over asthma, perhaps because they minimize symptoms and underestimate their impact, suggested Michael Wolf, a professor of medicine at Northwestern University’s Feinberg School of Medicine. “Older adults have a tendency to ignore difficulties with breathing,” noted Rachel Taliercio, a pulmonologist at the Cleveland Clinic. “Instead of thinking this could be asthma, they think, ‘I’m overweight, I’m out of shape, I’m getting older, and this is normal at this time of life.’ ”
- 09.15.2017 - CardiologyFeaturing: Charles Davidson, MD
- 09.15.2017 - CardiologyFeaturing: Charles Davidson, MD
- 09.15.2017 - CardiologyFeaturing: Mark Ricciardi, MD
- 09.07.2017 - Rheumatology
- Alumnus John Flanagan Establishes Stone Professorship in Honor of His Longtime Northwestern Physician09.06.2017Northwestern alumnus John R. Flanagan, ’58 MBA, has been supporting his alma mater for more than 40 years, making numerous gifts across Northwestern University’s campuses. Recently, as a part of We Will. The Campaign for Northwestern Medicine, Mr. Flanagan made an extraordinary gift to establish the Neil J. Stone, MD, Professorship at Northwestern University Feinberg School of Medicine. This endowed professorship honors Neil J. Stone ’66, ’68 MD, ’74 GME, ’75 GME, who serves as the Robert Bonow, MD, Professor of Medicine at Feinberg.
- 09.05.2017 - CardiologyFeaturing: Michael Severino, MD