Northwestern University Feinberg School of Medicine
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2018 Environmental Drivers of Aging: Proteostasis, Metabolism, and Signaling Conference

The 2018 Environmental Drivers of Aging: Proteostasis, Metabolism, and Signaling Conference was held on Friday, January 12, 2018. Below is information on that conference. Please check back in the Fall for information regarding next year's event!

Symposium Organizers:
Scott Budinger, MD, William E Balch, PhD, Navdeep Chandel, PhD, Alexander Misharin, MD, PhD,
Richard Morimoto, PhD, Karen Ridge, PhD, and Jacob Sznajder, MD

Registration is required to attend this event. Online registration is located here. There is no charge for registration.

Program Description

The goal of this conference is to understand whether and how key processes involved in biologic aging might be manipulated to reduce the risk of chronic disease later in life from varying biological perspectives.  Speakers in this conference are investigators that have contributed significantly to the improved understanding of aging biology to prevent or even reverse aging phenotypes. 

This conference will be of interest to researchers interested in understanding the intersection between aging biology, physiology and disease pathogenesis.

Related Program

The “23rd Annual Midwest Stress Response and Molecular Chaperone Meeting” is being held on Saturday, January 13, 2018, at the James L. Allen Center of the Evanston Campus of Northwestern University. This meeting will provide the opportunity for those interested in the areas of stress response, heat-shock proteins, and molecular chaperones to present their own work and learn from others working in this field.

 Speakers

Budinger

"Understanding Molecular Signatures of Aging"

Scott Budinger, MD
Ernest S. Bazley Professor and Chief, Pulmonary and Critical Care
Northwestern University

Research Website

Bowdish

“The Aging Microenvironment Dictates Monocyte Phenotype and Function”

 Dawn Bowdish, PhD
Associate Professor, Department of Pathology & Molecular Medicine, MG DeGroote Institute for Infectious Disease Research, McMaster Research Immunology Centre
McMaster University

Research Website

Campisi

"The Senescence Response as a Driver of Intrinsic and Extrinsic Signals of Aging"

 Judith Campisi, PhD
Professor, Buck Institute for Research on Aging
Senior Scientist, Lawrence Berkeley National Laboratory

Research Website

DeCabo

“Dietary Interventions for Healthy Aging”

 Rafael DeCabo, PhD
Senior Investigator & Chief
NIA Translational Gerontology Branch

Research Website
Gestwicki

“Targeting Protein-Protein Interactions in Chaperone Networks”

Jason Gestwicki, PhD
Professor, Institute for Neurodegenerative Diseases
University of Califirnia at San Francisco

Research Website

Haynes

“Age-Associated Deterioration and the Mitochondrial UPR”

Cole Haynes, PhD
Associate Professor, Molecular, Cell, and Cancer Biology
University of Massachusetts Medical School

Research Website

Morimoto

"The Biology of Proteostasis in Aging and Disease"

Rick Morimoto, PhD
Professor, Molecular Biosciences
Northwestern University

Research Website

niedernhofer

“Stress Response to Endogenous DNA Damage”

Laura Niedernhofer, MD, PhD
Associate Professor, Molecular Medicine
Scripps Florida

Research Website

Selman

"Aging and Pulmonary Fibrosis"

Moises Selman, MD
Director of Research
Instituto Nacional de Enfermedades Respiratorias

Research Website

Siders

"Functional Expansion of Proteostasis in the Vertebrate Secretory Pathway"

Richard N Sifers, PhD
Professor of Pathology & Immunology
Director of Operations, Center for Drug Discovery
Co-Director, Immunology Graduate Program
Baylor College of Medicine

Research Website

Session Chairs
Session 1 Ronald Kohanski, PhD
       Deputy Chair, Aging Biology, National Institute of Aging
Alexander Misharin, MD, PhD
     Assistant Professor of Medicine, Pulmonary and Critilca Care, Northwestern University

Session 2

William Balch, PhD
      Professor of Chemical Biology, The Scripps Research Insitute, California
Karen Ridge, PhD
      Professor of Medicine, Pulmonary and Critilca Care, Northwestern University

This meeting is supported by the National Institutes of Aging PPG Grant On Disordered Proteostasis as a Driver of Disease in the Aging Lung (1P01AG049665-01).

 Registration

Please click here to register for this meeting.  The registration deadline is Wednesday, January 3, 2018 at 11:59pm.

If you have problems accessing the link, please email Sean Campbell at seancampbell@northwestern.edu

 Schedule


8:00 AM Breakfast
8:30 AM Welcome

Scott Budinger, MD
Chief of Pulmonary and Critical Care in the Department of Medicine
Ernest S. Bazley Professor of Airway Diseases
Professor of Medicine and Cell and Molecular Biology
Northwestern University
8:35 AM The Biology of Proteostasis in Aging and Disease

Rick Morimoto, PhD
Professor
Molecular Biosciences, Northwestern University
9:10 AM Functional Expansion of Proteostasis in the Vertebrate Secretory Pathway

Richard Sifers, PhD
Professor of Pathology & Immunology, Director of Operations for the Center For Drug Discovery, Co-Director of the Immunology Graduate Program
Baylor College of Medicine
9:45 AM Targeting Protein-Protein Interactions in Chaperone Networks

Jason Gestwicki, PhD
Professor, Institute for Neurodegenerative Diseases
University of California at San Francisco
10:20 AM Morning Break
10:45 AM Stress Response to Endogenous DNA Damage

Laura Niedernhofer, MD, PhD
Associate Professor
Department of Molecular Medicine
The Scripps Research Institute (Florida Campus)
11:20 AM Dietary Interventions for Healthy Aging

Rafael DeCabo, PhD
Senior Investigator & Chief, Translational Gerontology Branch
National Institutes on Aging
12:00 PM Lunch Break
1:30 PM

Understanding the Molecular Signatures of Aging


Scott Budinger, MD

2:05 PM Aging and Pulmonary Fibrosis

Moises Selman, MD
Director of Research
Instituto Nacional de Enfermedades Respiratorias
2:40 PM Age-Associated Deterioration and the Mitochondrial UPR

Cole Haynes, PhD
Associate Professor
Molecular, Cell, and Cancer Biology
University of Massachusetts Medical School
3:15 PM Afternoon Break
3:30 PM The Aging Microenvironment Dictates Monocyte Phenotype and Function

Dawn Bowdish, PhD
Associate Professor, McMaster University
Canada Research Chair in Aging & Immunity
4:00 PM The Senescence Response as a Driver of Intrinsic and Extrinisic Signals of Aging

Judith Campisi, PhD
Professor, Buck Institute for Research on Aging  
Senior Scientist Lawrence Berkeley National Laboratory
4:35 PM Closing remarks

Scott Budinger, MD
4:45 PM Reception

 Accommodations

There are several hotels that are within walking from the conference venue.

Hampton Inn (.3 miles)
Speacial discounted rates are available at this hotel. Please choose between a Regular Room or a Suite.
Guest Speakers: Contact Sean Campbell or Kat Barnes to make your arrangements)
160 East Huron, Chicago, Illinois 60611
312.706.0888 (Contact Melissa Laberbera)

Cambria (.2 Miles)
166 East Superior Street, Chicago, Illinois 60611
312.787.6000

Hyatt Regency (0.3 miles)
633 North Clair Street, Chicago, Illinois 60611
312.787.1234

Courtyard Marriot (0.4 miles)
165 East Ontario, Chicago, IL 60611
312.573.0800

 Public Transportation

During rush hour (7-9am and 4-6pm) or inclement weather. The Chicago Transit Authority (CTA) offers train service to/from both O’Hare International and Midway airports can be the most reliable way to reach our campus.


During non-peak travel times, taxis or ride sharing services are also good options to travel to our campus.

CTA Service
 
Ventra Card
You will need a Ventra Card to use the train and bus in Chicago.  You can get a card online or by purchasing a card at the CTA station.  The fare is $5 for the train from O’Hare and $0.25 for the bus transfer (used within 2 hours of original fare).

Route from O’Hare

  1. From O’Hare International Airport Terminals 1, 2, or 3, follow signs that say “CTA Trains” or “Trains to City” which will take you to the O’Hare Blue Line station on the lower level.
  2. Take the Blue Line Train to the Clark/Lake (16th stop) and transfer to the Red Line heading to Howard station.  On the second train stop, Chicago Station, get off and go east on Chicago Avenue to Michigan Avenue, and head south to street of your hotel. (Superior, Huron, or Erie street,  ~0.3 miles)

OR

  1. Take the Blue Line Train and get off Chicago Avenue station (16th stop).  Take the CTA Bus #66 east to Navy Pier.  Get off on Superior, Huron, or Erie stop, depending on your hotel.

Route from Midway

  1. Midway International Airport, follow signs that say “CTA Trains” or “Trains to City” which will take you to the Midway Orange Line station located on the east side of the airport.
  2. Take any Orange line train to the State & Lake station to transfer to the Redline.  Take the Redline Train headed north to Howard.  Get off at the Chicago Avenue stop.  Go east on Chicago Avenue towards Michigan Avenue and head south of your hotel. (Superior, Huron, or Erie street,  ~0.3 miles)

 Campus Shuttle Bus Service

The Intercampus Shuttle runs between the Chicago and Evanston campus and runs Monday through Friday.  For the Evanston to Chicago schedule click here. For the Chicago to Evanston schedule click here.

The shuttle service is not available on Saturday to travel to the 23rd Stress Response and Molecular Chaperone meeting on January 13, 2018 at the Chicago Campus.  Please see the Public Transportation section and take CTA, taxi, or ride sharing services.  

 Campus Map

 Tourism and Attractions

Tourist Attractions Close to Northwestern University Chicago Campus

Art Institute of Chicago (1.2 miles)
111 South Michigan Avenue, Chicago
www.artic.edu

Museum of Contemporary Art (0.4 miles)
220 East Chicago Avenue, Chicago
mcachicago.org

Navy Pier (Entertainment Center, 1.2 miles)
600 East Grand Avenue, Chicago
navypier.com

John Hancock Building (Observatory and 95th Flr Restaurant, 0.4 miles)
875 North Michigan Avenue, Chicago
www.johnhancockcenterchicago.com

Shows in Chicago

Wicked
Beautiful
Hamilton
Turandot

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